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BIO 226W
Nazareth College
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Hypothyroidism
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Hypothyroidism
is a silent condition that affects 1.5 million American women. The disorder can
strike in the early twenties, and sometimes in the late teen years, but it is
most common in women over the age of 45. In fact, one
in ten women will be afflicted with Hypothyroidism by the age of 50. In general, thyroid
disorders, affect women more often than men; in the case of Hypothyroidism, women are
five times more likely than men to develop the disorder.
Hypothyroidism is considered a silent disease because its symptoms are related to aging and other
biological milestones, such as pregnancy and menopause. Its two main symptoms, fatigue and
weight gain, are easily blamed on aging, poor diet, lack of exercise, and other basic health
issues. Consequently, people often fail to talk to their doctor about their symptoms. In the
following paragraphs, you will find answers to important questions regarding Hypothyroidism. It is
my hope that this information may help you or a loved one learn that there is treatment for
what can appear to be simply fatigue.
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What is Hypothyroidism?
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Hypothyroidism is a disease of the thyroid, a small organ located in the
lower front of your neck. The
thyroid
is an integral part of healthy metabolism affecting such
things as your heart rate and the rate at which you burn calories.
When your thyroid produces the right amounts of hormones, your metabolism functions normally and
your overall health is maintained. However, when your thyroid cannot produce sufficient
quantities of thyroid hormones, your thyroid is considered to be "under active", and this condition
is called Hypothyroidism.
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What are the symptoms of
Hypothyroidism?
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Hypothyroidism develops slowly, and symptoms rarely appear immediately.
At first you may only feel tired and sluggish. However, as time passes, an under active
thyroid
can lead to a great number of health problems. The severity of hypothyroidism's symptoms is
dependent on the degree of hormone deficiency. Those who are severely deficient
in thyroid hormones will experience both a greater number and
greater effect of symptoms, while those with slight deficiency may
experience few symptoms that are not severe or obvious. Some of the following symptoms
can be easily confused with the effects of aging; however, they may also indicate a thyroid
deficiency:
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- Hoarse or husky voice
- The need to "clear your throat" often
- Difficulty swallowing
- Persistent dry or sore throat
- Hair loss/Thinning Hair
- Brittle nails
- A puffy face and/or eyes
- Pale, dry skin
- Increased sensitivity to the cold
- Chronically cold hands and feet
- Muscle weakness, cramps and/or stiffness
- Lack of energy
- Constant feeling of tiredness
- Unexplained weight gain
- Constipation
- Heavier than normal menstrual periods
- Elevated blood cholesterol levels
- Depression
- Moodiness/Irritability
- Forgetfulness/Slower thinking
- Inability to concentrate
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How is Hypothyroidism diagnosed?
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Until recently, doctors were unable to detect an under active
thyroid
until symptoms were quite advanced. Thankfully, a new test has been developed that can identify
the disorder much earlier--often before symptoms are even noticed. The preliminary test used
to diagnose thyroid disorders is commonly referred to as the TSH test. TSH is an abbreviation for
thyroid stimulating hormone; it is a chemical released by the pituitary gland that
stimulates the
thyroid to produce more thyroid hormone based on your body's specific
needs. When the level of TSH in the blood is high,
and the level of thyroid hormone is low, Hypothyroidism is diagnosed, because
it indicates that the body is telling the thyroid to produce more thyroid
hormones (as evidenced by the elevated amount of TSH in the blood) but
that the thyroid is unable to manufacture enough hormone to keep up with
the demand (as seen by the low thyroid hormone level in the blood). In a
healthy body, when TSH is released by the pituitary gland, into the blood
stream, the thyroid is able to respond quickly. It releases thyroid
hormones into the blood and creates a balance in the body that allows
metabolism to function efficiently, which leads to a person feeling of
"energized".
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How is Hypothyroidism treated?
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Once it has been determined that your thyroid is under active, a thyroid
hormone supplement can be prescribed. This medication is a synthetic hormone called
levothyroxine; levothyroxine is sold with the brand names Synthroid,
Levoxyl, and Levothroid. This oral
medication will most likely have to be taken daily for the rest of your life.
The symptoms of Hypothyroidism will subside soon after you begin levothyroxine treatment. The
medicine will gradually lower blood cholesterol levels and may reverse weight gained from the
disorder.
It may take a few months to determine the exact dosage that is needed to balance out your metabolism.
Your physician will require a subsequent TSH test to make sure that your body is receiving the
necessary amount of thyroid hormones that it needs for optimum health. Once the appropriate dosage is
determined, Levothyroxine users experience virtually no side effects.
Some endocrinologists recommend that women over age 60 be given a TSH test for Hypothyroidism at
every annual physical exam because it is quite prevalent in older women. Women who are pregnant
are also at risk of developing this disorder, thus many physicians advise routine TSH tests for
pregnant women.
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Complications of Hypothyroidism?
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If left untreated, an under active thyroid may cause problems in nearly
every organ system in your body; these complications will be dependent upon the severity of
your specific case. The cardiovascular system can have the effects of a
slowed heart rate and/or increased diastolic blood pressure. If the kidneys are affected you
may retain more water or notice edema (swelling). The liver can also be effected by the disorder
resulting in increased LDL (bad) cholesterol and increased triglycerides. Your thyroid may also
enlarge (a condition known as goiter) if treatment is not found, because the body constantly
attempts to stimulate the thyroid to make more hormones.
In women,
untreated hypothyroidism can
cause abnormally heavy periods, missed ovulation, decreased fertility, and missed menstrual
periods. Other systems of the body are affected, including the gastrointestinal tract, the
central nervous system, the musculoskeletal system, and the skin and hair. However, most of
these complications caused by lack of treatment or poor treatment are identical to the symptoms
that are listed above.
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Related Web Sites
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References
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- Shamon, Mary J. Living Well with Hypothyroidism: What your doctor doesn't tell you--
that you need to know. New York: Whole Care, 2000.
- Snyderman, Dr. Nancy. "The Healthy Woman." ABC Good Morning America, September 29, 1998.
File 648:TV and Radio Transcripts.
- Surks, Martin I. The Thyroid Book. Yonkers, N.Y.: Consumer Reports Books, 1993.
- American Academy of Family Physicians. Hypothyroidism-At Risk: Women and Seniors.
http://www.aafp.org/servlet/xmlPress?press_id=766. November 15, 2001.
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Created by: Nadine Weisbrod on
04/12/02
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