CHED Irvin Levy, Carmen Gauthier, Nicole Snyder  Monday, April 8, 2013 

967 - Towards the analysis of small molecule HIV-1 viral entry inhibitor with gp120 on a solid surface

Goodwell Nzou,, Stephen Tajc. Department of Chemistry and Biochemistry, Nazareth College, Rochester, New York 14618, United States

The number of people dying from HIV/AIDS infection continues to escalate throughout the world. There is a critical need for smaller, inexpensive molecules for the diagnosis of the virus to help minimize the proliferation of this pandemic. Currently, a rapid HIV test that utilizes antibodies is available for diagnosing an HIV infection1. However, a large antibody protein is less stable and cost more to produce large quantities than a small molecule with similar binding capabilities. This project is geared towards the exploration of NBD-556, which binds to the HIV-1 envelope glycoprotein gp1202. Understanding the solid surface binding capabilities of this small molecule HIV-1 viral entry inhibitor may lead to fast and affordable diagnosing tools for lower income areas both domestic and worldwide.

Monday, April 8, 2013 12:00 PM
Undergraduate Research Posters (12:00 PM - 02:30 PM)
Location: Morial Convention Center
Room: Hall D


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