CHED Irvin Levy, Carmen Gauthier, Nicole Snyder  Monday, April 8, 2013 

968 - Investigation of dipicolinic acid-derivatives using structural activity relationships

James J Chambers, jchambe2@mail.naz.edu, Stephen G Tajc. Department of Chemistry and Biochemistry, Nazareth College, Rochester, NY 14618, United States

Some bacteria spores release dipicolinic acid (DPA) is a naturally occurring compound released that is known to chelate to calcium, copper, cobalt and iron. DPA has multiple parts on the molecule that could be used for chelation, and although the location of the interaction has been extensively studied the binding could be optimized. Testing DPA and its derivatives with other cations will help to determine the optimal binding for cations and the essential aspects for optimization. Performing a structural activity relationship test on the DPA molecule will allow us to find compounds with better chelation as well as allow us to further understand the mechanism of binding allowing us to improve the binding capabilities.


Monday, April 8, 2013 12:00 PM
Undergraduate Research Posters (12:00 PM - 02:30 PM)
Location: Morial Convention Center
Room: Hall D

 

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